Weigh and Dispense with Precision: The Vital Role of Containment Isolators in the Pharmaceutical Industry

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ProSys Technology provides an expansive range of Containment products for the Pharmaceutical industry, custom designed and fabricated in-house for our global client base. Our proven designs have been successfully independently validated to protect operators and the surrounding area, down to single digit nanogram CPT (Containment Performance Target) levels, whilst handling the most potent of HPAPI’s (High Potent Active Pharmaceutical Ingredients). Engineering studies and ergonomic mock-up reviews available for the complete Isolator range upon request.

One of the most common Containment Isolator’s purpose is for weighing & dispensing. Even for this seemingly common operation, Isolators are able to posses unique designs to suit the process. ProSys Technology custom designs each individual Isolator to suit your specific process requirements.

The Weighing & Dispensing Isolator can be affected by the following:

  • Containment Performance Target or CPT (micrograms/m3 vs nanograms/m3)
  • Size of incoming material packaging being handled (large drums vs small pail size)
  • Other processes (slurry, liquid addition, milling etc.)

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Weighing/Dispensing Isolator using bag out ports for removal of product typically used for > 0.1 micrograms/m3 Containment Performance Target. 
Three chambers Weighing/Dispensing Isolator utilises an airlock for incoming product and materials, into a RTP system. Used for < 10 nanograms/m3 Containment Performance Target.
Drum lifters with inflatable seal interfaced used for large drums that cannot physically sit inside the Isolator.
Isolator used to weigh potent powder then dispense into a slurry tank outside the Isolator via split butterfly valve. Incoming powder enters via lower chamber.
A peristaltic pump** inside the Isolator moves liquid to container on scale for weighing then adding to powder for mixing inside the Isolator.
Potent powder** weighed then added to integrated mill within the Isolator

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**Peristaltic Pump: A Peristaltic pump, also commonly known as a roller pump, is a type of positive displacement pump used for pumping a variety of fluids.

**Potent Powder: Potent powder handling Isolators are designed to provide a cost-effective, safe handling environment for high potency drugs.

ProSys Technology approaches every project as our customer’s partner, to assist them in producing an Isolator system that is the best solution for their process and operators. Get in touch today to find out more!

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